NVIDIA Blackwell powers Cadence’s AI-driven engineering design

Cadence‘s new Millennium M2000 Supercomputer represents a significant leap in computational power for engineering and life sciences, featuring NVIDIA‘s Blackwell architecture to deliver up to 80x performance gains over CPU-based predecessors. This collaboration between NVIDIA and Cadence aims to accelerate breakthrough development in autonomous machines, drug discovery, semiconductor design, and data center optimization through massive parallel computing capabilities and specialized software optimizations.

The big picture: Cadence is launching a new supercomputer powered by NVIDIA’s Blackwell architecture that dramatically accelerates computational workflows for engineering and scientific applications.

• The Millennium M2000 Supercomputer integrates NVIDIA HGX B200 systems and RTX PRO 6000 Blackwell Server Edition GPUs, available for both cloud and on-premises deployment.
• Compared to previous CPU-based systems, the supercomputer delivers up to 80x higher performance for electronic design automation, system design, and life sciences workloads.

What they’re saying: The collaboration represents a significant joint investment in next-generation computing infrastructure and specialized software optimization.

• “This is years in the making,” Cadence CEO Anirudh Devgan said during a conversation with NVIDIA CEO Jensen Huang at CadenceLIVE. “It’s a combination of advancement on the hardware and system side by NVIDIA — and then, of course, we have to rewrite our software to take advantage of that.”
• Huang highlighted the broader implications: “AI is going to infuse into every single aspect of everything we do. Every company will be run better because of AI, or they’ll build better products because of AI.”

Why this matters: NVIDIA itself plans to purchase 10 Millennium Supercomputer systems based on its GB200 NVL72 platform, underscoring the technology’s strategic importance.

• “This is a big deal for us,” Huang stated. “We started building our data center to get ready for it.”

Key focus areas: The collaboration between NVIDIA and Cadence centers on three transformative technological domains.

• The companies are jointly developing AI factories, digital twins, and agentic AI capabilities.
• Huang described these AI factories as “a whole new type of factory that’s necessary” for the future of computing and industry.